|Nolvadex Patient Information|
|INFORMATION PRESENTED HERE IS INCOMPLETE, IT DOES NOT CONTAIN ALL INFORMATION ABOUT NOLVADEX AND DOES NOT REPLACE YOUR DOCTOR'S ADVICE. PLEASE CONSULT WITH A LICENSED PHYSICIAN BEFORE USING NOLVADEX®
|Chemical name: Tamoxifen|
|What NOLVADEX is used for|
|NOLVADEX is used to treat breast cancer. NOLVADEX blocks the actions of oestrogen. Oestrogen is a natural female sex hormone. In some types of breast cancer, oestrogen can help cancer cells to grow. Your doctor will have explained why you are being treated with NOLVADEX and told you what dose to take. Follow all directions given to you by your doctor. They may differ from the information contained in this leaflet. Your doctor may prescribe this medicine for another use. Ask your doctor if you want more information. NOLVADEX is not addictive.|
|Before you use NOLVADEX|
|When you must not use it
Do not use NOLVADEX if you are
pregnant, trying to become
pregnant or are breastfeeding.
We do not know if it is safe for you
to take it while you are pregnant. It
may affect your baby if you take it at
any time during pregnancy.
Your baby may take in NOLVADEX
from breast milk if you are
Do not use NOLVADEX if you are
allergic to tamoxifen or any of the
other ingredients in NOLVADEX.
Do not give NOLVADEX to
There is no experience of its use in
Do not take after the use by
(expiry) date printed on the pack.
It may have no effect at all, or worse,
an entirely unexpected effect if you
take it after the expiry date.
Do not take NOLVADEX if the
packaging is torn or shows signs of
Do not use it to treat any other
complaints unless your doctor tells
Do not give this medicine to
anyone else, even if they have the
same condition as you.
Before you start to use it
You must tell your doctor if:
1. you have any allergies to:
* tamoxifen, the active ingredient
* any of the other ingredients in
NOLVADEX listed at the end of
* other anti-oestrogen medicines
* any other medicines
* any other substances, such as
foods, preservatives or dyes.
If you have an allergic reaction, you
may experience a skin rash, hayfever,
difficulty breathing or feel faint.
2. you have or have ever had any
of these medical conditions:
* any unexplained vaginal bleeding
* problems with your blood
* liver problems.
It may not be safe for you to take
NOLVADEX if you have any of
Taking other medicines
Tell your doctor if you are taking
any other medicines, including:
* medicines used to thin your blood
* any medicines that you buy at the
chemist, supermarket or health
These medicines may affect the way
Your doctor or pharmacist can tell
you what to do if you are taking any
of these medicines.
If you have not told your doctor
about any of these things, tell them
before you take any NOLVADEX.|
|Follow all directions given to you
by your doctor or pharmacist
They may differ from the
information contained in this leaflet.
Your doctor or pharmacist will tell
you how many tablets you will need
to take each day.
If you do not understand the
instructions on the box, ask your
doctor or pharmacist for help.
How much to take
Your doctor will decide how much
NOLVADEX you need to take.
The usual dose is 20 mg of
NOLVADEX each day.
This is two 10 mg Nolvadex tablets
taken together or one 20 mg
Nolvadex-D tablet taken once a day.
Some people need to take 40 mg once
a day. Your doctor will tell you if
this is necessary.
Swallow your NOLVADEX whole,
with a full glass of water. Do not
chew or crush the tablets.
When to take it
Take NOLVADEX at about the
same time each day.
It does not matter if you take
NOLVADEX before, with or after
How long to take it
Continue taking NOLVADEX for as
long as your doctor or pharmacist
tells you to.
If you forget to take it
If you miss a dose, take it as soon
as you remember, as long as it is 12
hours before the next dose is due.
If it is less than 12 hours to the next
dose, do not take the dose you have
Do not double the dose to make up
for the dose that you missed.
If you are not sure what to do, ask
your doctor or pharmacist.
If you have trouble remembering
to take your medicine, ask your
pharmacist for some hints.|
|Immediately telephone your doctor
or pharmacist or the Poisons
Information Centre (telephone 13
11 26), or go to Accident and
Emergency at your nearest
hospital immediately if you think
that you or anyone else may have
taken too much NOLVADEX. Do
this even if there are no signs of
discomfort or poisoning.
If you take too much NOLVADEX
you may experience problems with
the rhythm of your heart.|
|While you are using it|
|Things you must do
Be sure to keep all your
appointments with your doctor so
your progress can be checked.
Tell any other doctors, dentists and
pharmacists who are treating you
that you are taking NOLVADEX.
If you are about to be started on
any new medicine, tell your doctor,
dentist or pharmacist that you are
If you go into hospital, please let
the medical staff know that you are
Things you must not do
Do not get pregnant while you are
Ask your doctor about reliable
methods of contraception while you
are taking NOLVADEX.
Do not take NOLVADEX to treat
any other complaints unless your
doctor tells you to.
Do not stop taking NOLVADEX,
or lower the dosage, unless you
have discussed this with your
Things to be careful of
Be careful driving or operating
machinery until you know how
NOLVADEX affects you.
Some patients may experience
dizziness or light headedness.|
|Tell your doctor or pharmacist as
soon as possible if you do not feel
well while you are taking
NOLVADEX helps most people with
breast cancer, but it may have
unwanted side effects in a few
All medicines can have side effects.
Sometimes they are serious, most of
the time they are not. You may need
medical treatment if you get some of
the side effects.
Ask your doctor or pharmacist to
answer any questions you may
Tell your doctor immediately if
you notice any of the following:
* unusual pain or pressure around
your pelvis, in your bones or
anywhere in your body
* excessive thirst
* swelling of the hands, ankles and
* any changes in your vision
* pain and reddening around the
* lumps anywhere in the body
* unusual tiredness, shortness of
breath and dizziness when
exercising, and looking pale
* frequent infection, fever, severe
chills, sore throat or mouth ulcers
* unexplained bruising
* yellowing of the skin or eyes,
dark coloured urine.
If you have any unusual vaginal
bleeding or other gynaecological
symptoms (such as pelvic pain or
pressure) when you are taking
NOLVADEX or anytime afterwards,
tell your doctor. This is because a
number of changes to the lining of
the womb (endometrium) may occur,
some of which may be serious and
could include cancer.
Tell your doctor immediately or go
to Accident and Emergency at
your nearest hospital if any of the
* rash, itching or hives
* swelling of the face, lips, tongue
* wheezing with difficulty
Increased risk of blood clots and
ovarian cysts (in premenopausal
women) have been seen with
These are serious side effects. You
may need urgent medical treatment.
Serious side effects are rare.
Tell your doctor if you notice any
of the following and they worry
* hot flushes
* nausea and vomiting
* unusual vaginal discharge
* any change in your periods
* itching around the vagina
* diarrhoea or constipation
* headache, dizziness or light
* hair thinning or hair loss.
These are all mild side effects of
Rarely an increased level of
triglycerides (increased levels of fats
in the blood) sometimes with
pancreatitis (pain or tenderness in the
upper abdomen) has been seen with
Tell your doctor or pharmacist if
you notice anything that is making
you feel unwell.
Some people may get other effects
while taking NOLVADEX.|
|After using it|
Keep your NOLVADEX tablets in
the blister pack until it is time to
If you take NOLVADEX out of the
blister pack it will not keep well.
Keep it in a cool dry place where
the temperature stays below 30
Do not store it or any other
medicine in the bathroom or near a
Keep it where young children
cannot reach it.
A locked cupboard at least
one-and-a-half metres above the
ground is a good place to store
Do not leave it on a window sill or
in the car on hot days.
Heat and dampness can destroy some
|Ask your pharmacist what to do
with any tablets you have left over
if your doctor tells you to stop
taking them, or you find that the
expiry date has passed.|
INFORMATION PRESENTED HERE IS INCOMPLETE, IT DOES NOT CONTAIN ALL INFORMATION ABOUT NOLVADEX AND DOES NOT REPLACE YOUR DOCTOR'S ADVICE. PLEASE CONSULT WITH A LICENSED PHYSICIAN BEFORE USING NOLVADEX®
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